1 bottle of Tamoxifen Citrate contains 100 tablets Each uncoated tablet contains: Tamoxifen Citrate 10mg
Tamoxifen is an antagonist of the estrogen receptor in breast tissue and is therefore used in the treatment of breast cancer.
Estrogen can promote the growth of breast cancer cells. Some breast cancers are classified as estrogen receptor-positive (also known as hormone sensitive), which means that they have a protein to which estrogen will bind. These breast cancer cells need estrogen to grow. Tamoxifen works against the effects of estrogen on these cells. It is often called an antiestrogen or a SERM (Selective Estrogen Receptor Modulator).
Tamoxifen is currently used for the treatment of both early and advanced estrogen receptor positive breast cancer in pre- and post-menopausal women. Additionally, it is the most common hormone treatment for male breast cancer. In men, Tamoxifen is sometimes used to treat gynecomastia that arises for example as a side effect of antiandrogen prostate cancer treatment. Tamoxifen is also used by bodybuilders to prevent or reduce drug-induced gynecomastia caused by the estrogenic metabolites of . Tamoxifen is also sometimes used to treat or prevent gynecomastia in sex offenders undergoing treatment by temporary chemical castration.
Tamoxifen may interact with other medicines. Let your doctor know about any medications you are taking, including non-prescribed drugs such as complementary therapies and herbal drugs.
Tamoxifen's selective estrogen activation effects can cause some serious side effects, including blood clots, stroke, and endometrial cancer. The most common side effects of tamoxifen are: increased tumor or bone pain, hot flashes, nausea, fatigue, mood swings, depression, headache, hair thinning, constipation, dry skin, loss of libido.
For patients with breast cancer, the recommended daily dose is 20 - 40mg. Dosages greater than 20mg per day should be given in divided doses (morning and evening).
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.